Author

Jessica A. Pettitt

Australian National UniversityORCID 0000-0002-0768-7920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Anne Brüstle· 2 shared Pål SætromiD· 2 shared Rebecca L. BucklandiD· 2 shared Alexandre RCom-H’Cheo-Forgues· 1 shared Anselm EndersiD· 1 shared Barbara van LooniD· 1 shared Bjørnar SporsheimiD· 1 shared Christopher Richard ParishiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

Anne Brüstle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Whole genome CRISPR knockout screen reveals ID3 as a key regulator of myeloma cell survival via TCF3 and c-MYC

Clara Andersson-Rusch, Md. Abu Hanif, Ingrid Quist-Løkken, Pål Sætrom, Miłosz Roliński, Johanna Fredrikke Nordstrand Moen, Naiara Campos Roman, Kristine Misund, Vidar Beisvåg, Per A. Aas, Barbara van Loon, Toril Holien

bioRxiv · Sep 9, 2025 · PreprintCancer Biology

Selective alteration to CD4 T cell differentiation by heterozygous IRF4L116R protects against neuroinflammation

Rebecca A. Jaeger, Nadia A. Roberts, Cynthia M. Turnbull, Sandali Seneviratne, Rebecca L. Buckland, Dominik Spensberger, Jessica A. Pettitt, Fiona D. Ballard, Anne Brüstle, Anselm Enders

This study shows that a heterozygous IRF4L116R mutation selectively impairs CD4 T cell differentiation into Th1, Th17, and Treg subsets, protecting against neuroinflammation without affecting overall T cell activation or memory.

bioRxiv · Jun 25, 2025 · PreprintImmunology

Alpha Synuclein Induced Immune Response Triggers Parkinson's Disease Like Symptoms

Rebekah G. Parkinson, Tony Xu, Jacob Martin, Zizheng Xian, Ilvana Ziko, Jessica A. Pettitt, Alexandre RCom-H’Cheo-Forgues, Rebecca L. Buckland, Sarah L. Gordon, Christopher Richard Parish, Anne Brüstle, Nathalie Dehorter

This study shows that autoimmune response to alpha-synuclein antigen causes Parkinson's disease-like symptoms in mice through immune cell infiltration and inflammation.

bioRxiv · May 27, 2024 · PreprintNeuroscience

The G2-phase enriched lncRNA SNHG26 is necessary for proper cell cycle progression and proliferation

Helle Samdal, Siv Anita Hegre, Konika Chawla, Nina‐Beate Liabakk, Per A. Aas, Bjørnar Sporsheim, Pål Sætrom

This study shows that SNHG26, a G2-phase enriched lncRNA, is necessary for cell cycle progression and proliferation, with effects on mitochondrial stress and gene expression.

bioRxiv · Feb 22, 2021 · PreprintMolecular Biology