Thomas Reiberger

Gut-derived ammonia modulates hypothalamic stress responses during viral infection

This study shows that gut-derived ammonia modulates hypothalamic stress responses during viral infection by increasing corticosterone levels and affecting antiviral responses.

Crosstalk between CD8+ T cells and systemic bile acid metabolism controls LCMV-induced immunopathology

This study shows that CD8+ T cells and bile acid metabolism interact during LCMV infection, with bile acids affecting T cell responses and immunopathology.

Purine nucleobases enhance CD8+ T cell effector function

This study identifies purine nucleobases as immunometabolites that enhance CD8+ T cell effector function by enabling a metabolic switch from de novo synthesis to salvage pathway.

Spatial single-cell interactome and niche-specific molecular signatures in alcohol-related liver disease

The paper uses spatial transcriptomics and single-cell data to identify niche-specific molecular signatures and signaling pathways in ALD cirrhosis, highlighting potential therapeutic targets.

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension

The paper identifies transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension using mouse models and patient data.