Author

Robert Zweigerdt

Medizinische Hochschule HannoverORCID 0000-0002-4656-0770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandra HaaseiD· 1 shared André ZeugiD· 1 shared Andreas KirschningiD· 1 shared Andreas Martens· 1 shared Birthe DorgauiD· 1 shared Evgeni G. PonimaskiniD· 1 shared Gerrit HilgeniD· 1 shared Gudrun Goehring· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alexandra HaaseORCID

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2 papers

Recent·Most cited

Transient Vascular Cell Integration and Intrinsic Media-Stimulated Endothelial Activation Reveal Diabetic Retinopathy Signatures in Human Retinal Organoids

Rozaliya Tsikandelova, Raphael Schettler, Matthew D. Teasdale, Joe Kelk, Veronica Boczonadi, Birthe Dorgau, Rafiqul Hussain, Reinhold J. Medina, Stephen White, Robert Zweigerdt, Lyle Armstrong, Gerrit Hilgen, Majlinda Lako

The paper develops vascular organoids that integrate into retinal organoids, revealing diabetic retinopathy-like gene expression patterns in endothelial-like cells.

bioRxiv · Oct 8, 2026 · PreprintNeuroscience

Targeted biallelic integration of an inducible Caspase 9 suicide gene for safer cellular therapies prevents development of drug-resistant escapees in human iPSCs

Stephanie Wunderlich, Alexandra Haase, Sylvia Merkert, Kirsten Jahn, Maximillian Deest, Silke Glage, Wilhelm Korte, Andreas Martens, Andreas Kirschning, André Zeug, Evgeni G. Ponimaskin, Gudrun Goehring, Mania Ackermann, Nico Lachmann, Thomas Moritz, , Ulrich Martin

This study introduces a biallelic inducible Caspase9 suicide gene system in hiPSCs to prevent drug-resistant escapees, showing no escapees in biallelic cells versus rare escapees in monoallelic cells.

bioRxiv · Sep 19, 2021 · PreprintMolecular Biology