Author

Stephanie Wunderlich

Medizinische Hochschule Hannover

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ulrich MartiniD· 3 shared Alexandra HaaseiD· 2 shared Sylvia MerkertiD· 2 shared Adrian SchwarzeriD· 1 shared André ZeugiD· 1 shared Andreas KirschningiD· 1 shared Andreas Martens· 1 shared Axel SchambachiD· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Ulrich MartinORCID

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Author profile →

3 papers

Recent·Most cited

Targeted biallelic integration of an inducible Caspase 9 suicide gene for safer cellular therapies prevents development of drug-resistant escapees in human iPSCs

Stephanie Wunderlich, Alexandra Haase, Sylvia Merkert, Kirsten Jahn, Maximillian Deest, Silke Glage, Wilhelm Korte, Andreas Martens, Andreas Kirschning, André Zeug, Evgeni G. Ponimaskin, Gudrun Goehring, Mania Ackermann, Nico Lachmann, Thomas Moritz, , Ulrich Martin

This study introduces a biallelic inducible Caspase9 suicide gene system in hiPSCs to prevent drug-resistant escapees, showing no escapees in biallelic cells versus rare escapees in monoallelic cells.

bioRxiv · Sep 19, 2021 · PreprintMolecular Biology

Reprogramming enriches for somatic cell clones with small scale mutations in cancer-associated genes

Maike Kosanke, Katarzyna Osetek, Alexandra Haase, Lutz Wiehlmann, Colin Davenport, Adrian Schwarzer, Felix F. Adams, Marc‐Jens Kleppa, Axel Schambach, Sylvia Merkert, Stephanie Wunderlich, Sandra Menke, Marie Dorda, Ulrich Martin

The paper shows that reprogramming enriches for mutations in cancer-associated genes in hiPSCs, potentially increasing tumor risk.

Molecular Therapy · Apr 5, 2021Peer-reviewedGenomics

The selection arena in early human blastocysts resolves the pluripotent inner cell mass

Manvendra Singh, Thomas J. Widmann, Vikas Bansal, José Luis Cortés, Gerald G. Schumann, Stephanie Wunderlich, Ulrich Martin, Jose Luis Garcia-Perez, Laurence D. Hurst, Zsuzsanna Izsvák

The paper reanalyzes single-cell transcriptomic data and in situ stains to reveal the presence of a transcriptomically homologous inner cell mass in human blastocysts, highlighting unique developmental and evolutionary features.

bioRxiv · Feb 4, 2019 · PreprintDevelopmental Biology