Cell BiologyProceedings of the National Academy of SciencesPeer-reviewed
Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets
Joost J.A.P.M. Wijnakker, Gijs J. F. van Son, Daniel Krueger…·Hans C. Clevers
The paper shows that Invasin-coated plates enable long-term 2D expansion of epithelial organoids from multiple species, offering an alternative to Matrigel/BME.