Gijs J. F. van Son

This study develops a human organoid model to investigate interferon-gamma's effects on alveolar epithelial cell regeneration, showing divergent impacts on AT1 and AT2 cells.

The paper shows that Invasin-coated plates enable long-term 2D expansion of epithelial organoids from multiple species, offering an alternative to Matrigel/BME.

The paper identifies four human tuft cell states, showing they function as radiation-resistant stem cells capable of regenerating the intestinal epithelium.