Daniel Krueger

The paper shows that Invasin-coated plates enable long-term 2D expansion of epithelial organoids from multiple species, offering an alternative to Matrigel/BME.

The paper identifies four human tuft cell states, showing they function as radiation-resistant stem cells capable of regenerating the intestinal epithelium.

This study uses optogenetic inhibition of Delta in Drosophila to show that Notch signaling exhibits digital behavior during tissue differentiation, with duration determining tissue-level responses and switch-like mechanisms at the cellular level.