Author
Royal Netherlands Academy of Arts and SciencesORCID 0009-0006-8832-3745Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Lulu Huang, Jochem H. Bernink, Amir Giladi…·Hans C. Clevers
The paper identifies four human tuft cell states, showing they function as radiation-resistant stem cells capable of regenerating the intestinal epithelium.
Joep Beumer, Maarten H. Geurts, Mart Matthias Lamers…·Hans C. Clevers
The paper uses CRISPR/Cas9 to generate mutant intestinal organoids and identifies TMPRSS2 as a critical host factor for multiple coronaviruses.
Maarten H. Geurts, Eyleen de Poel, Cayetano Pleguezuelos‐Manzano…·Hans C. Clevers
This study evaluates prime editing for modeling cancer mutations and repairing CFTR in intestinal organoids, showing its potential but also highlighting challenges in efficiency and off-target effects.