Author

Wade H. Berrettini

University of PennsylvaniaORCID 0000-0002-4733-2286Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Wade H. Berrettini2 papers · University of Pennsylvania

Biology Disciplines

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Genetics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Benjamin C. ReineriD· 3 shared Andrew E. WelleriD· 2 shared Gabriella Arauco‐Shapiro· 2 shared Glenn A. R. DoyleiD· 2 shared Gustavo TureckiiD· 2 shared Richard C. CristiD· 2 shared Alexander Samir HatoumiD· 1 shared Alicia Pigeon· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenetics

Benjamin C. ReinerORCID

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3 papers

Recent·Most cited

Acute opioid responses are modulated by dynamic interactions of Oprm1 and Fgf12

Paige M. Lemen, Yanning Zuo, Alexander Samir Hatoum, Price E. Dickson, Guy Mittleman, Arpana Agrawal A, Benjamin C. Reiner, Wade H. Berrettini, David George Ashbrook, Mustafa Hakan Gunturkun, Xusheng Wang, Megan K. Mulligan, Caleb J. Browne, Eric J. Nestler, Francesca Telese, , Hao Chen

This study identifies time-dependent epistatic interactions between Oprm1 and Fgf12 that modulate opioid-induced locomotion in mice and links Fgf12 to opioid behavior in humans.

eLife · Jul 29, 2026Peer-reviewedGenetics

Single-nuclei transcriptomics of schizophrenia prefrontal cortex primarily implicates neuronal subtypes

Benjamin C. Reiner, Richard C. Crist, Lauren Michelle Stein, Andrew E. Weller, Glenn A. R. Doyle, Gabriella Arauco‐Shapiro, Gustavo Turecki, Thomas N. Ferraro, Matthew R. Hayes, Wade H. Berrettini

This study uses single-nuclei transcriptomics to identify differentially expressed genes in specific neuronal cell types from schizophrenia patients, linking them to schizophrenia and bipolar GWAS loci.

bioRxiv · Jul 29, 2020 · PreprintNeuroscience

Restriction Enzyme Based Enriched L1Hs sequencing (REBELseq)

Benjamin C. Reiner, Glenn A. R. Doyle, Andrew E. Weller, Rachel N. Levinson, Esin Christine Namoglu, Alicia Pigeon, Gabriella Arauco‐Shapiro, Emilie Dávila Perea, Cyndi Shannon Weickert, Gustavo Turecki, Deborah C. Mash, Richard C. Crist, Wade H. Berrettini

REBELseq identifies Ta subfamily L1 retrotransposon insertions in neuronal DNA from postmortem brain samples, revealing differences in insertion prevalence across individuals.

bioRxiv · Aug 27, 2019 · PreprintGenetics