Author

Alec R. Koss

Northwestern UniversityORCID 0000-0002-4733-9007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Colleen R. ReczekiD· 1 shared Jenna L. E. BlumiD· 1 shared Karis B. D’AlessandroiD· 1 shared Navdeep S. ChandeliD· 1 shared Ram Prosad ChakrabartyiD· 1 shared Rogan A. GrantiD· 1 shared Shawn M. DavidsoniD· 1 shared Zachary L. SeboiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPhysiology

Colleen R. ReczekORCID

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1 paper

Recent·Most cited

Metformin inhibits mitochondrial complex I in intestinal epithelium to promote glycemic control

Zachary L. Sebo, Ram Prosad Chakrabarty, Rogan A. Grant, Karis B. D’Alessandro, Alec R. Koss, Jenna L. E. Blum, Shawn M. Davidson, Colleen R. Reczek, Navdeep S. Chandel

This study shows metformin lowers blood glucose by inhibiting intestinal mitochondrial complex I, increasing lactate and GDF15, and promoting glucose uptake.

bioRxiv · Oct 2, 2025 · PreprintPhysiology