Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView
Takamasa Kudo, Ana M. Meireles, Reuben M. Moncada, Yushu Chen, Ping Wu, Joshua Gould, Xiao‐Yu Hu, Opher S. Kornfeld, Rajiv Jesudason, Conrad Foo, Burkhard Höckendorf, Héctor Corrada Bravo, Jason P. Town, Runmin Wei, Antonio Rios, , Eric Lubeck
PerturbView enables highly multiplexed optical pooled screens in primary cells and tissues by improving barcode amplification, revealing regulators of NFκB signaling and enabling spatial transcriptomics integration.
Nature Biotechnology · Oct 7, 2024Peer-reviewedSystems Biology