Author

Macarena I. de la Fuente

University of MiamiORCID 0000-0002-9676-9329Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Michael E. IvaniD· 2 shared Adam M. SonabendiD· 1 shared Alexandra Alvarado Medina· 1 shared Alexandre WojcinskiiD· 1 shared Anatol Oleksijew· 1 shared Anna Jane Hudson· 1 shared Anna M. JermakowicziD· 1 shared Antonio IavaroneiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Michael E. IvanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations

Robert K. Suter, Anna M. Jermakowicz, Rithvik Veeramachaneni, Matthew D’Antuono, L.G. Zhang, Rishika Chowdary, Simon Kaeppeli, Madison Sharp, Pravallika Palwai, Vasileios Stathias, Grace Baker, Luz Clarita Ruiz, Winston M. Walters, Maria L. Cepero, Danielle M. Burgenske, , Nagi G. Ayad

The paper integrates single-cell RNA sequencing data with drug response signatures to identify drug-sensitive and resistant glioblastoma cell states and predict synergistic drug combinations.

Nature Communications · Jan 7, 2026Peer-reviewedCancer Biology

Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma

Deepa Seetharam, Jay S. Chandar, Christian Kieran Ramsoomair, Jelisah Desgraves, Alexandra Alvarado Medina, Anna Jane Hudson, Ava Amidei, Jesús Castro, Vaidya Govindarajan, Sarah Wang, Yong Zhang, Adam M. Sonabend, Mynor J. Mendez Valdez, Dragan Maric, Vasundara Govindarajan, , Ashish Harish Shah

This study shows targeting ZNF638 induces viral mimicry and enhances immune checkpoint inhibition in glioblastoma by increasing dsRNA signaling and PD-L1 expression.

Journal of Clinical Investigation · Mar 16, 2025Peer-reviewedCancer Biology