Isabella Eckerle

A human monoclonal antibody from hybrid immunity exhibits exceptional neutralization breadth against antigenically divergent contemporary Omicron JN.1 lineage variants

This paper identifies a monoclonal antibody from hybrid immunity that broadly neutralizes multiple Omicron variants by targeting conserved epitopes on the spike protein.

Age- and Virus-Specific Signatures of In Vitro Reconstituted Human Airway Epithelia in the Presence and Absence of Respiratory Viral Infections

This study compares age-specific immune responses to respiratory viruses in human airway epithelia, finding distinct SARS-CoV-2 signatures in children that may explain milder disease.

Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera

The paper compares SARS-CoV-2 antigenicity across assays and in human and animal model sera, finding similar immunodominance patterns and antigenic maps but differences in titer magnitude and assay-specific fold change.