Juan Manuel Carreño

Integrative Mapping of Pre-existing Immune Landscapes for Vaccine Response Prediction

Immunaut identifies distinct immunophenotypic responder groups shaped by baseline immune landscapes using a comprehensive LAIV dataset, advancing precision vaccinology and guiding personalized immunization strategies.

Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination

This study identifies non-neutralizing antibodies from vaccinated individuals that protect against SARS-CoV-2 in animal models, highlighting their role through Fc-mediated effector functions and conserved epitope binding.

Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera

The paper compares SARS-CoV-2 antigenicity across assays and in human and animal model sera, finding similar immunodominance patterns and antigenic maps but differences in titer magnitude and assay-specific fold change.