Marie F.A. Cutiongco

Macrophages promote collagen deposition through circadian regulation of fibroblasts

This study shows macrophages enhance collagen deposition in fibroblasts through circadian regulation, with M2 macrophages using PDGFA to strengthen circadian rhythms and increase collagen production.

Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells

The paper shows that acute chromatin decompaction increases nuclear stiffness in some cells but not others, depending on their ability to recompact chromatin.

Circadian and permanent pools of extracellular matrix co-exist in tendon tissue, but have distinct rates of turnover and differential responses to ageing

The paper uses stable isotope labeling and mass spectrometry to show that tendon ECM has circadian and permanent pools with distinct turnover rates, which change with age.

Interactive machine learning for fast and robust cell profiling

This paper introduces an interactive machine learning approach to optimize cell profiling pipelines by reducing cognitive load and improving segmentation quality compared to trial-and-error methods.