Author
University of California, San FranciscoORCID 0000-0002-4894-919XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Kwang Il Jung, Savannah McKenna, Lu Jiang…·Bumsuk Hahm
This study shows that SPL in lung epithelial cells reduces influenza severity by enhancing innate defenses and altering cell type proportions.
Ranjha Khan, María L. Allende, Ehtesham Khalid…·Julie Deane Saba
The paper shows pyridoxine supplementation improves SPLIS symptoms in a patient and mouse model by reducing S1P levels and enhancing SPL activity.
Holly C. Beale, Victor Tse, J.Y. Lee…·Anne Michele Slavotinek
The paper identifies a pathogenic splice site variant in DEGS1 causing aberrant splicing and loss of enzyme activity in individuals with HLD18.
Camila D. Arcuschin, Kamin Kahrizi, Rosalyn W. Sayaman…·Denise P. Muñoz
The paper identifies ThPOK/ZBTB7B as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype by suppressing metastatic pathways.
Adam Majcher, Kathrin Buder, Ranjha Khan…·Thorsten Hornemann
This paper investigates SPLIS, showing that S1P accumulation in SPL-deficient cells leads to nephrotoxicity, which can be mitigated by Fasudil.