Author

Kathrin Buder

Universitätsklinikum TübingenORCID 0000-0002-5425-0772Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Adam Majcher· 1 shared Adrian F. SchnelliD· 1 shared Alexander Henrici· 1 shared Andreas PichlmairiD· 1 shared Carina C. de Oliveira ManniD· 1 shared Dorota KmiećiD· 1 shared Indra BekereiD· 1 shared Julia MergneriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

Adam Majcher

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Structural Basis for OAS2 Regulation and its Antiviral Function

Veronika Merold, Indra Bekere, Stefanie Kretschmer, Adrian F. Schnell, Dorota Kmieć, Rinu Sivarajan, Katja Lammens, Rou Liu, Julia Mergner, Julia Teppert, Maximilian Hirschenberger, Alexander Henrici, Sarah Hammes, Kathrin Buder, Marcus Weitz, , Carina C. de Oliveira Mann

This study reveals the structural basis of OAS2 regulation and its antiviral function, showing how it discriminates RNA length and restricts viruses like coronaviruses.

Molecular Cell · May 23, 2025Peer-reviewedBiochemistry

Disrupted Sphingosine-1-Phosphate Homeostasis Drives Nephrotoxicity in Sphingosine-1-Phosphate Lyase Insufficiency Syndrome (SPLIS)

Adam Majcher, Kathrin Buder, Ranjha Khan, Julie Deane Saba, Thorsten Hornemann

This paper investigates SPLIS, showing that S1P accumulation in SPL-deficient cells leads to nephrotoxicity, which can be mitigated by Fasudil.

bioRxiv · Jan 21, 2025 · PreprintPhysiology