Author

Rika Sakuma

Hyogo Medical UniversityORCID 0000-0002-4907-3046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Akiyoshi ShimuraiD· 2 shared Bun AoyamaiD· 2 shared Gen ShinozakiiD· 2 shared Hieu Dinh NguyeniD· 2 shared Ilgin Genc· 2 shared Kyosuke YamanishiiD· 2 shared Nathan James PhuongiD· 2 shared Nipun GorantlaiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Akiyoshi ShimuraORCID

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2 papers

Recent·Most cited

A genome-wide catalog of sites where peripheral DNA methylation reflects the brain

Shota Nishitani, Shizhong Han, Takaya Ishii, Akiyoshi Shimura, Nathan James Phuong, Asahi Kato, Meagan Chambers, Tao Wang, Makoto Isozaki, Yoshifumi Higashino, Takahiro Yamauchi, Satoshi Kawajiri, Hidetaka Arishma, Toshiaki Kodera, Hirochika Imoto, , Gen Shinozaki

The paper identifies brain-peripheral DNA methylation sites (BrESS) that consistently predict brain methylation across tissues, showing they are not linked to disease heritability.

bioRxiv · Oct 24, 2026 · PreprintNeuroscience

Zuranolone mitigates delirium-like bispectral EEG changes, behavioral deficits, and neuroinflammation across surgical and inflammatory mouse models and age groups

Bun Aoyama, Shota Nishitani, Kyosuke Yamanishi, Hieu Dinh Nguyen, Rika Sakuma, Takaya Ishii, Yukiko Ikeda, Tsuyoshi Nishiguchi, Ilgin Genc, Nathan James Phuong, Nipun Gorantla, Tomoteru Seki, Akiyoshi Shimura, Takashi Kawano, Gen Shinozaki

bioRxiv · May 21, 2026 · PreprintNeuroscience