Author

Ali Pejmun Haghighi

Buck Institute for Research on AgingORCID 0000-0002-4928-3609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Gary K. Scott· 2 shared Alexander M. WalteriD· 1 shared Ammar AlyiD· 1 shared Andreas Till GrasskampiD· 1 shared Anthony W. McCarthyiD· 1 shared Astrid G. PetzoldtiD· 1 shared Christine Brigitte BeuscheliD· 1 shared David OwaldiD· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Gary K. Scott

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 3, 2022

A retrograde GCN2/eIF2α, but ATF4 independent, mechanism maintains synaptic strength under acute amino acid scarcity at the NMJ

Grant Kauwe, Megumi Mori, Edward H. Liao…·Ali Pejmun Haghighi

The paper investigates how GCN2/eIF2α signaling maintains synaptic strength during acute amino acid scarcity at the Drosophila NMJ, showing ATF4 is dispensable and the pathway acts retrogradely from muscle to motoneuron.

DOI 10.1101/2022.11.03.515133

Drosophilaexperimental assay

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Molecular BiologybioRxivPreprintOct 17, 2022

N6-Adenosine Methylation of a Single Site in SARS-CoV-2 5'-UTR Promotes Translation

Ammar Aly, Gary K. Scott, Mario R. Calderon, Ali Pejmun Haghighi

The paper shows that a single m6A modification in SARS-CoV-2 5'-UTR enhances translation by destabilizing a stem loop and increasing accessibility.

4 citations

virusstatistical model

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NeuroscienceNature CommunicationsPeer-reviewedMar 6, 2019

Rapid active zone remodeling consolidates presynaptic potentiation

Mathias A. Böhme, Anthony W. McCarthy, Andreas Till Grasskamp…·Alexander M. Walter

The paper identifies a molecular mechanism for presynaptic plasticity involving rapid remodeling of active zone modules, which sustains neurotransmitter release potentiation over time.

132 citationstop 1%

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