Hamid Band

A novel RNA-binding activity of ECD contributes to U5 snRNP stability and pre-mRNA splicing

This study identifies ECD's RNA-binding activity and shows it stabilizes U5 snRNP and is essential for pre-mRNA splicing.

Orai1 is required for Ca2+-dependent plasma membrane repair and mechanoadaptation

This study identifies Orai1 and EHD2 as essential for Ca2+-dependent plasma membrane repair and mechanoadaptation in response to mechanical injury and bacterial toxins.

PRMT5 as an Epigenetic Target for Group 3 (MYC-driven) Medulloblastoma

This study identifies PRMT5 as an epigenetic regulator of MYC transcription and oncogenic programs in Group 3 medulloblastoma, showing that its inhibition suppresses tumor growth and prolongs survival in mouse models.

ECD, a novel androgen receptor target promotes prostate cancer tumorigenesis by regulating glycolysis

This study identifies ECD as a novel androgen receptor target that promotes prostate cancer by enhancing glycolysis and oncogenic traits.

ECD co-operates with ERBB2 to promote tumorigenesis through upregulation of unfolded protein response and glycolysis

This study shows ECD and ERBB2 cooperate in breast cancer by enhancing unfolded protein response and glycolysis through direct mRNA binding and increased glucose uptake.

Hyperglycemic state and fluid shear stress affect metastatic breast cancer cell migration via focal adhesion kinase

This study shows high glucose and fluid shear stress together enhance metastatic breast cancer cell migration, mediated by focal adhesion kinase.