Developmental BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress
Mitzy A. Cowdin, Tuli Pramanik, Shelby R. Mohr-Allen…·Ondine B. Cleaver
This paper shows that Lats1/2 are essential for vascular remodeling and response to shear stress in embryonic endothelial cells, leading to vascular defects and embryonic lethality.
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