Functional divergence of WWC family proteins in human endothelial cells
Tuli Pramanik, Austin Mills, Ondine B. Cleaver
This study identifies distinct roles for WWC2 and WWC3 in human endothelial cells, showing WWC3's dominance in Hippo signaling and WWC2's role in VEGF signaling, with both affecting EC proliferation and migration.
bioRxiv · Aug 24, 2026 · PreprintCell Biology