Author

Long‐Sheng Chang

Abigail Wexner Research InstituteORCID 0000-0002-5178-2992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Janet L. OblingeriD· 2 shared Lai Man Natalie WuiD· 2 shared Adam P. JonesiD· 1 shared Alona MuzikanskyiD· 1 shared Bingyu Xiu· 1 shared Brian WeissiD· 1 shared Daichi Hagita· 1 shared Daniel von Allmen· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Janet L. OblingerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

YAP-TEAD-driven CPA4 promotes NF2-deficient meningioma growth

Kentaro Mineji, Katerina Petrosky, Ryosuke Otsuji, Yasuhide Makino, Yuji Kibe, Eita Uchida, Daichi Hagita, Neha Singaravelan, Yukitomo Ishi, Shigeru Yamaguchi, Long‐Sheng Chang, Samantha Gadd, Rintaro Hashizume

This study identifies CPA4 as a YAP-TEAD-driven effector in NF2-deficient meningioma, showing its role in tumor growth and sensitivity to TEAD inhibitors.

bioRxiv · Aug 7, 2026 · PreprintCancer Biology

Single-cell and Spatial Omics Reveals Region-Specific Plasticity and Therapeutic Vulnerabilities in Metastatic High-Risk Neuroblastoma

Lai Man Natalie Wu, Janet L. Oblinger, Dazhuan Eric Xin, Rohit Rao, Feng Zhang, Mike Adam, Oscar F. Lopez‐Nunez, Sara Szabo, Daniel von Allmen, Long‐Sheng Chang, Brian Weiss, Qing Richard Lu

This study uses single-cell and spatial omics to identify plasticity and therapeutic targets in metastatic high-risk neuroblastoma.

Science Advances · Jul 17, 2026Peer-reviewedCancer Biology

Enhanced Tumor Control and Hearing Loss Prevention Achieved with Combined Immune Checkpoint Inhibitor and Anti-VEGF Therapy in Vestibular Schwannoma Model

Simeng Lu, Zhenzhen Yin, Limeng Wu, Yao Sun, Jie Chen, Lai Man Natalie Wu, Janet L. Oblinger, Day Caven Blake, Bingyu Xiu, Lukas David Landegger, Richard Seist, William W. Ho, Adam P. Jones, Alona Muzikansky, Konstantina M. Stanković, , Lei Xu

Nature Communications · Feb 11, 2026Peer-reviewedCancer Biology