The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline
Elisabeth A. Marnik, Miguel Vasconcelos Almeida, Patricia Giselle Cipriani, George Chung, Edoardo Caspani, Emil Karaulanov, Hin Hark Gan, John Zinno, Ida J. Isolehto, Fridolin Kielisch, Falk Butter, Catherine S. Sharp, Roisin M. Flanagan, Frederic X. Bonnet, Fabio Piano, , Dustin L. Updike
The paper identifies LOTR-1, a C. elegans protein with LOTUS and Tudor domains, which interacts with ZNFX-1 to regulate small RNA processing in the germline.
PLoS Genetics · Jun 3, 2022Peer-reviewedDevelopmental Biology