Author

Yuxiang Wang

Case Comprehensive Cancer CenterORCID 0000-0002-5275-1709Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yuxiang Wang1 paper · Queen's University

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Zhenghe WangiD· 2 shared Adam M. KresakiD· 1 shared Athar KhaliliD· 1 shared Berkley E. GryderiD· 1 shared Christopher D. McFarlandiD· 1 shared Jacob G. ScottiD· 1 shared Jeff MaltasiD· 1 shared Madeline BedrockiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Zhenghe WangORCID

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2 papers

Recent·Most cited

Cancer BiologyGenes & DiseasesPeer-reviewedAug 1, 2026

Simultaneous inhibition of PI3Kα and EZH1/2 suppresses PIK3CA helical domain mutated CRC by promoting IL15-mediated activation of NK cells

Yuxiang Wang, Yamu Li, Zhenghe Wang, 赵弋清

This study shows that combining PI3Kα and EZH1/2 inhibitors suppresses PIK3CA-mutated CRC by enhancing IL15-mediated NK cell activation.

DOI 10.1016/j.gendis.2026.102405

mouseexperimental assay

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Cancer BiologyGenes & DiseasesPeer-reviewedSep 3, 2025

In Vivo Multiplexed Modeling Reveals Diverse Roles of the TBX2 Subfamily and Egr1 in Ras-Driven Lung Adenocarcinoma

Athar Khalil, Trang Dinh, Meaghan Parks…·Christopher D. McFarland

The paper develops a multiplexed mouse model to study TBX2 subfamily and Egr1 roles in Ras-driven lung cancer, finding Egr1 loss significantly increases tumor size and suggests immune dysregulation.

DOI 10.1016/j.gendis.2025.101840

mousebulk RNA-seq

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