Yosuke Tanaka

This study shows midbody inheritance in HSCs delays re-entry into the next cell cycle but does not affect lineage potential.

This study tracks Gfi1 expression dynamics during hematopoietic development and identifies its role in defining EHT and HSC potency.

This study shows that MECOM mutations impair DNA binding and functionally antagonize GATA2, promoting leukemia and inhibiting mast cell differentiation.

This study identifies Plcl1 as a regulator of calcium dynamics in hematopoietic stem cells, affecting their function during aging and stress.

This study shows that ASXL1 mutations in mice promote atherosclerosis by dysregulating innate immunity through impaired inhibition of NF-κB signaling.

This paper establishes expanded potential stem cells (EPSCs) from mouse blastomeres and shows they can contribute to both embryo proper and trophoblasts in chimeras.