Girish Deshpande

The paper shows that Wunen(s) inhibit Hedgehog signaling in Drosophila PGCs by affecting Smo localization and lipid metabolism, preventing premature clumping.

This study investigates the role of Caspar in Drosophila melanogaster, showing it regulates primordial germ cell count and identity through interactions with Smaug and effects on Oskar protein levels.

This study shows low-affinity binders can modulate high-affinity interactions through herd regulation, impacting biological processes like sex determination and signaling thresholds.

The paper shows that Zelda and CLAMP are required for proper germline/soma distinction in Drosophila embryos by regulating PGC determinant sequestration and preventing their spread to somatic nuclei.

The paper identifies Nup107 as a mediator of female sexual differentiation through its regulation of Dsx and BMP signaling in Drosophila.

The paper investigates the role of Satb2 in regulating zygotic genome activation and developmental transitions during vertebrate embryogenesis, showing distinct maternal and zygotic functions.

The paper shows that CLAMP and Zelda work together to drive zygotic genome activation in Drosophila by enhancing chromatin accessibility and promoting transcription.

The paper identifies DMon1 as a novel regulator in the brain-gonad axis, showing its role in female germline maturation through neuronal control of insulin production.