Author

Tzu-Jou Chen

Rockefeller UniversityORCID 0000-0002-5328-2000Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Ari HakimiiD· 1 shared Beatrice D. ZhangiD· 1 shared Cameron G. RobertsiD· 1 shared Charlotte R. WayneiD· 1 shared Christopher Austin KlebanoffiD· 1 shared Ekaterina V. VinogradovaiD· 1 shared Henry SanfordiD· 1 shared Hiroyuki KojimaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Ari HakimiORCID

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1 paper

Recent·Most cited

Cysteine reactivity profiling links metabolic rewiring to the dysfunctional human T cell proteome.

Hiroyuki Kojima, Charlotte R. Wayne, Luis F. Somarribas Patterson, Henry Sanford, Tzu-Jou Chen, Ya-Hui Lin, Joshua David Schoenfeld, Lisa H.F. McGary, Yanting Chen, Korbinian Nepomuk Kropp, Beatrice D. Zhang, Jahan A. Rahman, Tiffany L. Zhang, Nathalie Ropek, Cameron G. Roberts, , Ekaterina V. Vinogradova

In chronically stimulated human T cells, suppressed oxidative metabolism and nucleotide loss accompany MAP2K4 activation. Inhibiting MAP2K4 (with the MKK4/7 inhibitor BSJ-04-122) restored tumor-cell killing in vitro.

bioRxiv · Oct 2, 2026 · PreprintImmunology✦ In-depth digest