Author

Pooja Patel

Fox Chase Cancer CenterORCID 0000-0002-5345-0158Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Pooja Patel2 papers

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Ferrier· 1 shared A. Glasgow· 1 shared A. Mellon· 1 shared Adam C. Martyn· 1 shared Adam HefeliD· 1 shared Adèle C. GreeniD· 1 shared Alexander DobroviciD· 1 shared Amit M. OzaiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

A. Ferrier

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2 papers

Recent·Most cited

BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance

Ksenija Nesic, John J. Krais, Yifan Wang, Cassandra J. Vandenberg, Pooja Patel, Kathy Qi Cai, Tanya Todorova Kwan, Elizabeth Lieschke, Gwo‐Yaw Ho, Holly E. Barker, Justin Bedő, Silvia Casadei, Andrew Farrell, Marc R. Radke, Kristy Shield‐Artin, , Lyndal S. Edwards

This study identifies secondary splice-site mutations in BRCA1 that drive exon skipping and PARP inhibitor resistance in ovarian and breast cancer.

Molecular Cancer · Aug 5, 2024Peer-reviewedGenetic & Genomic Medicine

RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis

Adam Hefel, Masayoshi Honda, Nicholas M. Cronin, Kailey Harrell, Pooja Patel, Maria Spies, Sarit Smolikove

This study identifies unique roles of RPA complexes in C. elegans meiosis, showing RPA-2 is essential for replication and repair, while RPA-4 inhibits RAD-51 and promotes apoptosis.

Nucleic Acids Research · Dec 29, 2020Peer-reviewedGenetics