Author

Mervyn P.H. Mol

Leiden University Medical CenterORCID 0000-0002-5380-5393Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Christine L. MummeryiD· 2 shared Richard P. DavisiD· 2 shared Andrea Chatrian· 1 shared Benjamin B. JohnsoniD· 1 shared Benoît Samson-Couterie· 1 shared Berend J. van MeeriD· 1 shared Ehsan RazaghiiD· 1 shared Elsa Sorman Paulsson· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Christine L. MummeryORCID

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2 papers

Recent·Most cited

A simplified co-culture reveals altered cardiotoxic responses to doxorubicin in hPSC-derived cardiomyocytes in the presence of endothelial cells

Marcella Brescia, James Gallant, Andrea Chatrian, Paul Keselman, Elsa Sorman Paulsson, Mervyn P.H. Mol, Rickard Sjögren, Karine Raymond, Valeria V. Orlova, Kalpana Barnes, Richard Wales, Jonas Austerjost, Michael W. Olszowy, Christine L. Mummery, Berend J. van Meer, Richard P. Davis

This study shows that endothelial cells enhance doxorubicin-induced cardiotoxicity in co-cultures with cardiomyocytes, challenging the focus on cardiomyocytes alone.

Stem Cell Reports · Feb 12, 2026Peer-reviewedPharmacology & Toxicology

Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening

Tessa de Korte, Benjamin B. Johnson, Georgios Kosmidis, Benoît Samson-Couterie, Mervyn P.H. Mol, Ruben W.J. van Helden, Ehsan Razaghi, Louise François, Viviana Meraviglia, Loukia Yiangou, Tom Kuipers, Hailiang Mei, Milena Bellin, Stefan R. Braam, Shushant Jain, , Richard P. Davis

This study develops scalable 3D cardiac microtissues for high-throughput drug screening, showing reproducible drug responses and identifying 17 drugs that rescue arrhythmic phenotypes.

Trends in biotechnology · Dec 18, 2025Peer-reviewedCell Biology