Patrick C.A. van der Wel

This study uses solid-state NMR to examine how MW8 antibodies bind to the fuzzy coat of HTT exon 1 fibrils, revealing structural and dynamic effects on the fibrils.

This study uses high-speed atomic force microscopy to directly observe secondary nucleation in huntingtin amyloid formation, revealing dynamic processes and the role of flanking segments.

This study uses solid-state NMR to investigate the conformational dynamics and interactions of high-molecular weight hyaluronic acid in a hydrated environment.

The paper determines the atomic structure of mutant huntingtin exon 1 fibrils using integrative analysis and molecular dynamics simulations combined with experimental data.