Greeshma Jain

This study uses solid-state NMR to examine how MW8 antibodies bind to the fuzzy coat of HTT exon 1 fibrils, revealing structural and dynamic effects on the fibrils.

This study uses high-speed atomic force microscopy to directly observe secondary nucleation in huntingtin amyloid formation, revealing dynamic processes and the role of flanking segments.

The paper determines the atomic structure of mutant huntingtin exon 1 fibrils using integrative analysis and molecular dynamics simulations combined with experimental data.