Author

Prasanna Babu Araveti

Boston UniversityORCID 0000-0002-5441-3826Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander A. GimelbrantiD· 2 shared Boris Ν. KholodenkoiD· 2 shared Igor KramnikiD· 2 shared Oleksii S. RukhlenkoiD· 2 shared Shivraj M. YabajiiD· 2 shared Suruchi LataiD· 2 shared Vadim ZhernovkoviD· 2 shared William R. BishaiiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Alexander A. GimelbrantORCID

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2 papers

Recent·Most cited

IFN and IFN mimetics prevent IFN-I-mediated TB susceptibility by regulating iron metabolism and lipid peroxidation

Prasanna Babu Araveti, Shivraj M. Yabaji, Muhammad Zainul Arifin, Suruchi Lata, Yuriy O. Alekseyev, Alexander A. Gimelbrant, William R. Bishai, Vadim Zhernovkov, Oleksii S. Rukhlenko, Boris Ν. Kholodenko, Igor Kramnik

This study identifies how IFN and mimetics prevent TB susceptibility by modulating iron metabolism and lipid peroxidation in macrophages.

bioRxiv · Jul 7, 2026 · PreprintImmunology

Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility

Shivraj M. Yabaji, Vadim Zhernovkov, Prasanna Babu Araveti, Suruchi Lata, Oleksii S. Rukhlenko, Salam Al Abdullatif, Arthur Vanvalkenburg, Yuriy O. Alekseyev, Qicheng Ma, Gargi Dayama, Nelson C. Lau, William Evan Johnson, William R. Bishai, Nicholas A. Crossland, Joshua David Campbell, , Igor Kramnik

This study identifies Myc dysregulation in macrophages as a driver of TB susceptibility by linking lipid peroxidation and IFN-I pathway hyperactivity.

bioRxiv · Mar 5, 2024Immunology