Shivraj M. Yabaji

This study identifies how IFN and mimetics prevent TB susceptibility by modulating iron metabolism and lipid peroxidation in macrophages.

This paper describes a mouse model of post-primary pulmonary tuberculosis that simulates hematogenous spread to the lungs and allows study of lung-specific TB mechanisms.

This study shows that senolytic drugs reduce tuberculosis progression in mice by eliminating senescent lung myeloid cells that promote disease.

This paper introduces a protocol for 3D multiplexed immunohistochemistry using Opal-TSA conjugated fluorescent dyes to enhance imaging of pulmonary TB lesions in mouse tissues.

This study identifies Myc dysregulation in macrophages as a driver of TB susceptibility by linking lipid peroxidation and IFN-I pathway hyperactivity.