David A. Baker

Dynamic phosphorylation of the Plasmodium falciparum Myosin A motor regulates motor speed and is important for asexual replication

This study shows that phosphorylation of Plasmodium falciparum MyoA at Ser19 dynamically regulates motor speed and is essential for asexual replication.

Prex1 controls glucose homeostasis by limiting glucose uptake and mitochondrial metabolism in liver through GEF-independent regulation of Gpr21

This study shows Prex1 regulates glucose homeostasis by reducing glucose uptake and mitochondrial metabolism in the liver, independent of its catalytic activity, through Gpr21 inhibition.

Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development

This study shows that PP7 is essential for early ring-stage development in Plasmodium falciparum but not for erythrocyte invasion.

CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation

The paper investigates the roles of CDC50 orthologues in Plasmodium falciparum, showing CDC50B modulates merozoite egress via GC interaction while CDC50C is essential for trophozoite maturation and haemoglobin processing.

Plasmodium falciparum guanylyl cyclase-alpha and the activity of its appended P4-ATPase domain are essential for cGMP synthesis and blood stage egress