Author

Kirsty MacLellan‐Gibson

Babraham InstituteORCID 0000-0002-6734-4452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Aaran VijayakumaraniD· 1 shared Adam T. McCormackiD· 1 shared Ajeian Jila· 1 shared Analle Abuammar· 1 shared Andrew J. MurrayiD· 1 shared Anna G. RobertsiD· 1 shared Christopher GodbehereiD· 1 shared Christopher K. E. BleckiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Aaran VijayakumaranORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication

Aaran Vijayakumaran, Christopher Godbehere, Analle Abuammar, Sophia Y. Breusegem, L. R. Hurst, Nobuhiro Morone, Jaime Llodrá, Melis T. Dalbay, Niaj Mohammad Tanvir, Ajeian Jila, Kirsty MacLellan‐Gibson, Christopher O’Callaghan, Esben Lorentzen, Wei Qiu, Christopher K. E. Bleck, , Vito Mennella

This study reveals a communication axis between motile cilia, rootlets, and mitochondria in respiratory epithelium, enhancing ciliary motility and ATP production.

Cell Reports · Jul 1, 2026Peer-reviewedCell Biology

Prex1 controls glucose homeostasis by limiting glucose uptake and mitochondrial metabolism in liver through GEF-independent regulation of Gpr21

Julia Y. Chu, Elpida Tsonou, Polly A. Machin, Kirsty MacLellan‐Gibson, Anna G. Roberts, Stephen A. Chetwynd, Adam T. McCormack, John C. Stephens, Elisa Benetti, Gemma K. Kinsella, David A. Baker, David C. Hornigold, Heidi C. E. Welch

This study shows Prex1 regulates glucose homeostasis by reducing glucose uptake and mitochondrial metabolism in the liver, independent of its catalytic activity, through Gpr21 inhibition.

bioRxiv · Apr 14, 2025 · PreprintPhysiology