Marie Held

BeatRatePy quantifies beat rate, contraction, and speed from label-free cardiac imaging data, showing consistent performance across different systems and datasets.

This study investigates the role of lysosomal Ca2+ signaling in heart rhythm and atrial function, finding that NAADP pathway inhibition affects SAN pacemaker activity and cAMP production in atrial myocytes.

This study identifies FDA-approved compounds that inhibit ExoU, a virulence factor in Pseudomonas aeruginosa, and shows their efficacy in reducing corneal infection severity in multiple models.

The paper compares the intracellular replication of different Salmonella pathovariants in human macrophages, finding that bloodstream-associated variants replicate more efficiently than global epidemic isolates.

This paper introduces scpImaging, a computational pipeline that uses microscopy data to detect multiplets and improve quality control in single-cell proteomics.

This study identifies the molecular mechanisms of Eut BMC assembly in Salmonella, revealing a 'Shell-first' pathway and the role of EutQ in cargo encapsulation and BMC formation.

This study attempts to use antisense inhibition to analyze gene function in an obligate symbiosis but concludes it is not feasible due to holobiont growth in response to antisense treatment.

This study uses light sheet fluorescence microscopy to track cell fate and morphological development in kidney organoids over 15 hours.