BioengineeringNature Cardiovascular ResearchPeer-reviewed
A Drug-Elicitable Alternative-Splicing Module (DreAM) for Tunable AAV Expression and Controlled Myocardial Regeneration
17 citationstop 2%
Author
Zhan Chen
Peking UniversityORCID 0000-0002-5542-675XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2024-2025 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 41 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Molecular BiologybioRxivPreprint
An all-in-one AAV vector for cardiac-specific gene silencing by an adenine base editor
Zhanzhao Liu, Luzi Yang, Yuhan Yang…·Yuxuan Guo
This study shows that single-AAV delivery of base editors can achieve effective cardiac gene silencing with higher success rates than dual-AAV systems.
3 citations - PhysiologybioRxivPreprint
Myocardial infarction creates a critical time window for AAV gene therapy
Gonglie Chen, Yueyang Zhang, Zhan Chen…·Yuxuan Guo
This paper shows that myocardial infarction creates a time window where AAV gene therapy is more effective in mice, improving gene expression and therapeutic outcomes when administered three days post-infarction.
DOI 10.1101/2024.06.10.597311