Quentin Amossé

The paper uses spatial transcriptomics and proteomics to show that Alzheimer's disease inflammation peaks in white matter, driven by lipid and carbonyl stress, and is linked to cognitive decline.

The paper examines microglial, inflammatory, and oligodendrocyte dynamics in Alzheimer's disease stages, finding early neuroinflammation impairs oligodendrocytes while late stages show partial recovery.

This study investigates how hippocampal AD pathology affects striatal dopamine release and locomotion through chemogenetic manipulation in AD rat models.

This study identifies cell type-specific immune alterations in bipolar disorder brains, showing reduced proinflammatory microglia and metabolic/immune dysregulation in astrocytes.

The paper shows TSPO expression increases in activated microglia in rodent models but not in human neurodegenerative diseases, indicating species-specific differences in TSPO function.