Yu Huining Sun

This study shows that specific pseudouridines in the U2 branch site recognition region affect branch site recognition during pre-mRNA splicing in yeast.

SpaceSequest provides a unified pipeline for analyzing spatial transcriptomics data from multiple platforms, enabling standardized processing, analysis, and visualization.

CompBioAgent provides a user-friendly tool powered by LLMs to explore scRNA-seq data through natural language queries and visualizations.

xOmicsShiny is an R Shiny application that enables cross-omics data analysis and pathway mapping with visualization and analytical tools.

ScaleSC provides a GPU-accelerated single-cell RNA-seq analysis pipeline with 20x speedup and scalability for large datasets.

The paper reanalyzes sperm chromatin structure in mice, finding that prior studies were contaminated by cell-free chromatin, and identifies open loci associated with early development.

OmicsView provides an interactive platform for analyzing omics data, enabling researchers to explore disease pathology and identify biomarkers using preprocessed datasets.

The paper shows that ribosomes guide piRNA production from mRNAs in 3UTRs after translating upstream long ORFs, revealing a conserved mechanism for piRNA biogenesis.

The paper develops a cost-effective rRNA depletion method for avian species, enabling RNA-seq and ribosome profiling by using custom-designed oligos, and applies it to chickens and mice.

The paper uses single-molecule long-read sequencing to identify conserved long RNA profiles in sperm and reveals a post-transcriptional selection mechanism shaping these profiles in mice and humans.