Author

Katarzyna Chojnowska

Gdańsk Medical UniversityORCID 0000-0002-5571-6618Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:batch correction / integration· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Jakub MieczkowskiiD· 5 shared Natalia H. FilipowicziD· 5 shared Anna KosteckaiD· 4 shared Arkadiusz PiotrowskiiD· 4 shared Hanna DaviesiD· 4 shared Jan Piotr DumanskiiD· 4 shared Łukasz SzylbergiD· 4 shared Marcin JąkalskiiD· 4 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenetic & Genomic Medicine

Jakub MieczkowskiORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 17, 2026

Spatial Transcriptomics of TNBC tumours and corresponding lymph node metastasis reveals immune hubs driven by TNF/NF-κB signalling of TMSB4X and CD74 expressing cells.

Adrian Perdyan, Urszula Ławrynowicz, Maciej Jaśkiewicz…·Jakub Mieczkowski

The paper uses spatial transcriptomics to identify immune hubs in TNBC lymph node metastases driven by TMSB4X and CD74, revealing spatially expanded inflammatory networks and myeloid-endothelial signaling.

DOI 10.64898/2026.03.15.711865

humanspatial transcriptomics

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Genetic & Genomic MedicinemedRxivPreprintOct 4, 2024

Beyond Tumors: Reduced survival linked to pathogenic PIK3CA and TP53 post-zygotic variants in the uninvolved breast tissue of recurrent cancer patients

Maria Andreou, Katarzyna Chojnowska, Natalia H. Filipowicz…·Arkadiusz Piotrowski

The paper identifies pathogenic post-zygotic variants in normal breast tissue of poor-prognosis cancer patients, linking them to reduced survival and disease recurrence.

DOI 10.1101/2024.10.04.24313634

humanwhole-exome sequencing

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GenomicsInternational Journal of CancerPeer-reviewedJun 8, 2024

Prelude to Malignancy: A Gene Expression Signature in Normal Mammary Gland from Breast Cancer Patients Suggests Pre-tumorous Alterations and Is Associated with Adverse Outcomes

Maria Andreou, Marcin Jąkalski, Katarzyna Duzowska…·Arkadiusz Piotrowski

4 citations

humanbulk RNA-seq

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Genetic & Genomic MedicineScientific ReportsPeer-reviewedApr 24, 2024

Loss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases

Magdalena Wójcik, Ulana Juhas, Elyas Mohammadi…·Jan Piotr Dumanski

The paper investigates LOY in TME leukocytes, finding higher LOY frequency in Tregs and its association with immune checkpoint receptor expression.

23 citationstop 4%

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintMar 31, 2022

Size matters - the impact of nucleus size on results from spatial transcriptomics

Elyas Mohammadi, Katarzyna Chojnowska, Michał Bieńkowski…·Jakub Mieczkowski

This study investigates how nucleus size affects spatial transcriptomics results and introduces CSDI to improve accuracy in analyzing consecutive tissue slices.

DOI 10.1101/2022.03.31.486657

humanspatial transcriptomics

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