Author

Maggie A. Middleton

University of TorontoORCID 0000-0002-5577-3479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Darrell DesveauxiD· 2 shared David S. GuttmaniD· 2 shared Pauline W. WangiD· 2 shared Alexandre MarteliD· 1 shared Amy Huei-Yi Lee· 1 shared Anastasia BaryshnikovaiD· 1 shared Brenda J. Andrews· 1 shared Cedoljub Bundalovic-TormaiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenomics

Darrell DesveauxORCID

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Author profile →

2 papers

Recent·Most cited

Predictive Modeling of Pseudomonas syringae Virulence on Bean using Gradient Boosted Decision Trees

Renan N. D. Almeida, Michael Greenberg, Cedoljub Bundalovic-Torma, Alexandre Martel, Pauline W. Wang, Maggie A. Middleton, Syama Chatterton, Darrell Desveaux, David S. Guttman

This paper uses gradient boosted decision trees to predict virulence of Pseudomonas syringae isolates on bean using genomic data, finding that PG3 strains are more host-specific than PG2 strains.

PLoS Pathogens · Jul 25, 2022Peer-reviewedGenomics

Yeast Genomic Screens Identify Kinesins as Potential Targets of the Pseudomonas syringae Type III Effector, HopZ1a

Amy Huei-Yi Lee, D. Patrick Bastedo, Timothy Lo, Maggie A. Middleton, Ji-Young Youn, Inga Kireeva, Jee Yeon Lee, Sara Sharifpoor, Anastasia Baryshnikova, Jianfeng Zhang, Pauline W. Wang, Sergio G. Peisajovich, Michael Constanzo, Brenda J. Andrews, Charles M. Boone, , David S. Guttman

The paper identifies HopZ1a, a T3SE from Pseudomonas syringae, as an acetyltransferase that targets plant kinesins to disrupt microtubule networks through yeast genetic and interaction screens.

bioRxiv · Jul 9, 2018 · PreprintMicrobiology