Author

Valeria Cagno

Centre Hospitalier Universitaire VaudoisORCID 0000-0002-5597-334XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Caroline TappareliD· 2 shared Francesco StellacciiD· 2 shared Gregory MatheziD· 2 shared Aleksandar AntanasijeviciD· 1 shared Anaïs HubartiD· 1 shared Arnaud Charles‐Antoine ZwygartiD· 1 shared Arunima Muliyil· 1 shared Charlotte Deloizy· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

Caroline TapparelORCID

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3 papers

Recent·Most cited

A pan-respiratory virus attachment inhibitor with high potency in human airway models and in vivo

Gregory Mathez, Paulo Jacob Silva, Vincent Carlen, Charlotte Deloizy, Clémentine Prompt, Anaïs Hubart, Joana Rocha‐Pereira, Marie Galloux, Ronan Le Goffic, Francesco Stellacci, Valeria Cagno

This paper develops a broad-spectrum antiviral compound that inhibits multiple respiratory viruses in human airway models and in vivo.

Science Advances · Aug 1, 2025Peer-reviewedMicrobiology

Enterovirus A71 adaptation to heparan sulfate comes with capsid stability tradeoff

Han Kang Tee, Simon Crouzet, Arunima Muliyil, Gregory Mathez, Valeria Cagno, Matteo Dal Peraro, Aleksandar Antanasijevic, Sophie Clément, Caroline Tapparel

This study shows that EV-A71 adapts to heparan sulfate by losing pH-dependent uncoating, which compromises capsid stability and affects viral fitness in vivo.

eLife · Dec 23, 2024Peer-reviewedMicrobiology

A novel anti-influenza combined therapy assessed by single cell RNA-sequencing

Chiara Medaglia, Ilya Kolpakov, Yong Zhu, Samuel Constant, Song Huang, Arnaud Charles‐Antoine Zwygart, Valeria Cagno, Emmanouil T. Dermitzakis, Francesco Stellacci, Ioannis Xénarios, Caroline Tapparel

This study evaluates a combined anti-influenza therapy using single cell RNA sequencing to show its effectiveness in inhibiting viral replication across different epithelial cell types.

bioRxiv · Jul 27, 2021 · PreprintGenomics