Author

Kailash Gulshan

Cleveland State UniversityORCID 0000-0002-5598-7370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Annette BellariD· 1 shared Anthony J. HorakiD· 1 shared Ashutosh PrinceiD· 1 shared C. Alicia TraughberiD· 1 shared Daniela S. AllendeiD· 1 shared David W. StreemiD· 1 shared Emily HuangiD· 1 shared Isabella JamesiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Annette BellarORCID

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2 papers

Recent·Most cited

FDA-approved drug library screen identifies antidepressants, antimicrobials, anti-COPD, and anti-CVD agents as blockers of NLRP3 inflammasome and sepsis in a sex-dependent manner.

Kara Timinski, Ashutosh Prince, Kalash Neupane, Swati Sharma, Nilam Bhandari, Mariam R. Khan, Yavar Shiravand, C. Alicia Traughber, Zackery Raquepaw, Kailash Gulshan

The paper screens FDA-approved drugs to identify those that block NLRP3 inflammasome activation and sepsis, with sex-dependent efficacy.

bioRxiv · Jul 29, 2026 · PreprintCell Biology

Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury

Venkateshwari Varadharajan, Iyappan Ramachandiran, William J. Massey, Raghav Jain, Rakhee Banerjee, Anthony J. Horak, Megan R. McMullen, Emily Huang, Annette Bellar, Shuhui Wang Lorkowski, Kailash Gulshan, Robert Nathaniel Helsley, Isabella James, Vai Pathak, Jaividhya Dasarathy, , Jonathan Mark Brown

This study shows that MBOAT7 loss of function in hepatocytes causes ethanol-induced liver injury by disrupting lysosomal biogenesis and autophagic flux.

eLife · Dec 27, 2023Peer-reviewedMolecular Biology