Identification of RNF114 as ADPr-Ub reader through non-hydrolysable ubiquitinated ADP-ribose
Max S. Kloet, Chatrin Chatrin, Rishov Mukhopadhyay, Bianca D. M. van Tol, Rebecca Smith, Sarah A. Rotman, Rayman T.N. Tjokrodirijo, Kang Zhu, Andrii Gorelik, Lucy Maginn, P.R. Elliott, Peter A. van Veelen, Dragana Ahel, Ivan Ahel, Gerbrand J. van der Heden van Noort
The paper identifies RNF114 as a specific reader of ubiquitinated ADP-ribose using a chemoproteomics approach and validates its interaction with the modified molecule.
Nature Communications · Jul 9, 2025Peer-reviewedMolecular Biology