Author
Leiden University Medical CenterORCID 0009-0007-4878-8385Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Marlieke L.M. Jongsma, Erik Bos, Lennert Janssen…·Ilana Berlin
The paper investigates VAP family tether selectivity and dynamics at membrane contact sites, revealing distinct MCS footprints and compensatory mechanisms in cellular homeostasis.
Yingjie Zhong, Anna E. George, Roman I. Koning…·Ilana Berlin
The paper identifies MARCKSL1 as a regulator of extracellular vesicle secretion pathways through a CRISPR activation screen and functional studies.
Leonard R. Pelgrom, Marjolein Quik, José Javier Fernández…·Bart Everts
This study identifies O-GlcNAcylation and reduced glycolysis as key factors in Th2 polarization by dendritic cells, showing their role in immune synapse regulation and TCR signaling.
Max S. Kloet, Chatrin Chatrin, Rishov Mukhopadhyay…·Gerbrand J. van der Heden van Noort
The paper identifies RNF114 as a specific reader of ubiquitinated ADP-ribose using a chemoproteomics approach and validates its interaction with the modified molecule.
Stephan Scherpe, Vito Pol, Raymond Kooij…·Ayşegül Sapmaz
This paper introduces Huib32, a selective USP32 inhibitor, and two activity-based probes that modulate endosomal processes and provide tools for studying USP32 in cancer and neurodegenerative diseases.
Jorn E. Stok, Sander B. van der Kooij, Dennis Gravekamp…·Annemarthe G. van der Veen
This study shows that vault RNAs enhance viral replication by facilitating the nuclear export of ELAVL1 and hnRNP C, which are required for efficient viral replication.
Max S. Kloet, Rishov Mukhopadhyay, Rukmini Mukherjee…·Gerbrand J. van der Heden van Noort
The paper develops covalent probes to target Legionella pneumophila effector enzymes, demonstrating their effectiveness in capturing DupA through in vitro testing and structural analysis.