Author

Sasha A.T. McDowell

University of British ColumbiaORCID 0000-0002-5666-9710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:Drosophila· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Michael D. GordoniD· 2 shared Molly StanleyiD· 2 shared Grace Davis· 1 shared Hanjie JiangiD· 1 shared Jacqueline GuilleminiD· 1 shared Jeffrey A. RiffelliD· 1 shared Jinfang LiiD· 1 shared Josefina Inés del MármoliD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Michael D. GordonORCID

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3 papers

Recent·Most cited

Molecular logic of pheromone recognition enables rational design of insect behavior modulators

Sukjin S. Jang, Sasha A.T. McDowell, Pramod KC, Marija Simjanoska, Sanjana Mandala, Xiao Zhang, Hanjie Jiang, Philip A. Cole, Jeffrey A. Riffell, Qinheng Zheng, Josefina Inés del Mármol

This paper decodes the structural logic of pheromone recognition in silkmoths to design small molecules that disrupt insect mating behavior.

bioRxiv · May 30, 2025 · PreprintNeuroscience

Taste cells expressing Ionotropic Receptor 94e reciprocally impact feeding and egg laying in Drosophila

Jacqueline Guillemin, Viktoriya Li, Grace Davis, Kayla Audette, Jinfang Li, Meghan Jelen, Sasha A.T. McDowell, Samy Slamani, Liam Kelliher, Michael D. Gordon, Molly Stanley

This study identifies IR94e-expressing gustatory receptor neurons in Drosophila that suppress feeding and enhance egg laying in response to amino acids.

bioRxiv · Jan 23, 2024 · PreprintNeuroscience

A molecular mechanism for high salt taste in Drosophila

Sasha A.T. McDowell, Molly Stanley, Michael D. Gordon

The paper identifies IR7c as a key receptor for high salt taste in Drosophila, showing it works with co-receptors to detect cation non-selective salts and can convert sodium-selective receptors to non-selective ones.

Current Biology · Jun 29, 2022Peer-reviewedNeuroscience