Author
University of SussexORCID 0000-0002-5689-5363Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Tom Powell, George G. B. Brown, Rachal M. Allison…·William H. Gittens
The paper shows that Top3 activity moves Holliday junctions from Spo11 hotspots to convergent transcription sites, where crossover resolution occurs during meiosis.
Luz María López Ruiz, Jon Alexander Harper, Dominic Johnson…·Matthew J. Neale
The paper models how Tel1-mediated feedback shapes Spo11-DSB formation in yeast, showing local inhibition leads to genome-wide DSB redistribution.
Luz María López Ruiz, Dominic Johnson, William H. Gittens…·Matthew J. Neale
The paper shows that extending meiotic prophase reduces DSB clustering by allowing chromosomal domains to reach similar Spo11-DSB potential.
George G. B. Brown, William H. Gittens, Rachal M. Allison…·Matthew J. Neale
The paper introduces CC-seq, a method to map Spo11 DNA double-strand breaks with nucleotide-resolution in S. cerevisiae meiotic cells.