Author

Shashank Tripathi

Indian Institute of Science BangaloreORCID 0000-0002-5702-9248Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abinaya KaliappaniD· 4 shared Rohan NarayaniD· 4 shared Santhosh Kambaiah NagarajiD· 3 shared Mansi SharmaiD· 2 shared Rajesh Thangavel YadaviD· 2 shared Shailly TomariD· 2 shared Adolfo García‐SastreiD· 1 shared Akhila B Rai· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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4 shared papersMicrobiology

Abinaya KaliappanORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Broad heterologous protection against Influenza A viruses by an adjuvant-free modular mucosal T-cell vaccine platform.

Rajesh Thangavel Yadav, Mansi Sharma, Santhosh Kambaiah Nagaraj, Rohan Narayan, Abinaya Kaliappan, Uma Shanmugasundaram, Rahul Chavan, Akhila B Rai, Rashmi Rai, Thottethodi Subrahmanya Keshava Prasad, Suryaprakash R. Sambhara, Rachit Agarwal, S.K. Tripathi

This paper describes a modular, adjuvant-free mucosal vaccine platform that elicits broad T cell immunity against multiple Influenza A virus strains.

bioRxiv · Jun 5, 2026 · PreprintBioengineering

An Oral Combination therapy against SARS-CoV-2 based on Synergistic Action of Auranofin and Remdesivir.

Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi

This paper shows that combining Auranofin and Remdesivir synergistically inhibits SARS-CoV-2 in vitro and in animal models.

bioRxiv · Dec 19, 2025 · PreprintMicrobiology

Differential modulation of Interferon and Cell Death Responses defines Human vs Avian Influenza A Virus Strain-Specific Virulence and guides Combination Therapy.

Mansi Sharma, Abinaya Kaliappan, Rajesh Thangavel Yadav, Rohan Narayan, Shachee Swaraj, Guojun Wang, Adolfo García‐Sastre, Shashank Tripathi

This study identifies strain-specific virulence mechanisms in IAV and proposes a combination therapy using Oseltamivir and Baricitinib to reduce inflammation and improve survival in a murine model.

bioRxiv · Jul 31, 2025 · PreprintMicrobiology

Activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease with antiviral efficacy in murine infection model

Shweta Choudhary, Sanketkumar Nehul, Santhosh Kambaiah Nagaraj, Rohan Narayan, Shalja Verma, Swati Sharma, Annu Kumari, Ruchi Rani, Ankita Saha, Debabrata Sircar, Abinaya Kaliappan, Shashank Tripathi, Gaurav Kumar Sharma, Pravindra Kumar, Shailly Tomar

This study identifies DUB inhibitors that target SARS-CoV-2 PLpro, inhibiting its proteolytic activity and restoring immune responses in a mouse model.

bioRxiv · Nov 11, 2022 · PreprintMicrobiology