Zeno Messi

This paper shows that a minimal mechanical model of an actomyosin network can spontaneously polarize and move through balanced contractility and adhesion, without external cues or complex signaling.

This paper shows that cell cycle oscillations in a polarity network allow cells to switch polarity states in response to morphogenetic cues by modulating feedback and stability.

The paper identifies human-specific features of telencephalic patterning in early development using single-cell transcriptomics and spatial imaging, showing delayed ventral SHH signaling and enhanced anterior FGF signaling compared to mice.